Information on this page, including unit offerings, is from the 2020 academic year.
|Organisational Unit||Medical, Molecular and Forensic Sciences|
|Teaching Timetables||Murdoch S2
|Description||How do organisms generate energy? How do they make the building blocks for new cells? These questions are at the heart of biochemistry and will be explored in this unit across a wide range of organisms. The basic structure of cells and the mechanisms by which they function will be examined, followed by a detailed study of the key pathways of energy generation and biosynthesis. The laboratory components will also develop core skills in biochemical analysis.|
|Unit Learning Outcomes||Knowledge
On completion of this unit, you should be able to demonstrate a broad and coherent understanding of:
1. The cellular machinery that enables the functioning of essential biochemical processes.
2. The major pathways of energy metabolism and biosynthesis across a range of different organisms.
3. The mechanisms of metabolic regulation at the individual enzyme and pathway level.
On completion of this unit, you should be able to demonstrate the following skills effectively:
4. Biochemical techniques relevant to the determination of metabolite levels and enzyme activity in biological samples.
5. The appropriate handling, analysis and presentation of biochemical data.
On completion of this unit, you should be able to demonstrate confidence and competence in applying knowledge and skills to practice by:
6. Relating changes in biochemical activity and metabolite levels to explain the molecular basis of organ and organism function.
|Timetabled Learning Activities||Lectures: 3 hours per week, laboratories: 6 x 3 hours.|
|Unit Learning Experiences||The approach to learning in this unit is to use the lectures to provide a clear framework for the study of biochemistry. Students are encouraged to look beyond the lecture content to extend their learning, with relevant references provided at the end of each lecture to acts as a guide. The unit is divided into four inter-related modules which cover (1) the core cellular machinery that underpins biochemistry; how cells use this machinery to both (2) extract energy from macromolecules and (3) build new molecules; (4) integration of biochemical pathways and the application of biochemistry to clinical diagnosis. Laboratory classes show students how to generate biochemical data and provide them with the skills to accurately interpret and report their results. Data handling skills as well as core concepts from lectures and are then reinforced in online activities. Throughout the semester, students are encouraged to participate in LMS-based discussions, which are moderated by the teaching team.|
|Assessment||Assessment task 1: Laboratory reports (x6)
Alignment to ULLOs 2, 4, 5, 6
Word length 1500 (approx.. 250 words/report)
Weighting 30% (5% per report)
Due Date: approximately fortnightly throughout semester
Marking time: 15 min/report
Assessment task 2: Mid-semester test
Alignment to ULLOs 1, 2, 3, 5
Duration: 1 hour
Due Date: Mid-semester
Marking time: 15 min/exam paper
Assessment task 3. Final exam
Alignment to ULLOs 1, 2, 3, 6,
Duration: 2 hours
Due Date: End of Semester
Marking time: 15 min/exam paper
|Prerequisites||BIO152 Cell Biology/Foundations of Cell and Molecular Biology/Foundations of Cell Biology|
|Exclusions||Students who have successfully completed BMS261 Human and Comparative Biochemistry or BIO270/BIO247 Biochemistry I may not enrol in this unit for credit.|
|Previously||2015: 'Biochemistry I'|
|Appears in these Courses/Majors:
see individual structures for context
|Appears in these Minors||Organic and Biological Chemistry
|Internet Access Requirements||Murdoch units normally include an online component comprising materials, discussions, lecture recordings and assessment activities. All students, regardless of their location or mode of study, need to have access to and be able to use computing devices with browsing capability and a connection to the Internet via Broadband (Cable, ADSL or Mobile) or Wireless. The Internet connection should be readily available and allow large amounts of data to be streamed or downloaded (approximately 100MB per lecture recording). Students also need to be able to enter into online discussions and submit assignments online.|