Information on this page, including unit offerings, is from the 2020 academic year.
Omics Technologies and Bioinformatics (BIO309)
|Organisational Unit||Medical, Molecular and Forensic Sciences|
|Teaching Timetables||Murdoch S1
|Description||Bioinformatics sits at the interface of biology and information science and is now a fundamental skill that is highly sought after throughout the life sciences, including the medical, agricultural and biological disciplines. This unit will provide an introduction to the challenges of analysing large biological data sets, including whole genome sequences, generated by cutting-edge omics technologies. Students will acquire practical competence in the effective use of bioinformatics tools through case studies and develop an understanding of bioinformatics workflows and methodologies.|
|Unit Learning Outcomes||On successful completion of the unit students should be able to:
1. Understand the fundamentals of key biotechnologies that are essential for molecular level biological research;
2. Accurately identify and apply correct biotechnologies into effective and independent experiments for any level/domain of life science research;
3. Describe clearly bioinformatics methods and data analytical workflows for modern -omics experiments;
4. Identify proper analytical methods and analyse independently complicated omics datasets from various sources;
5. Design new workflows consisting of existing bioinformatics tools to solve unique problems arising in specific datasets;
6. Develop practical skills and ability for performing future systematic biology studies.
|Timetabled Learning Activities||Lectures: 2 hours per week x 12 week; 2 hours per tutorial x 11.
All offerings of this unit include the equivalent of 46 hours of structured learning.
|Unit Learning Experiences||Lectures in this unit will firstly cover theoretical and applied content related to pivotal biotechnologies that have been the driving force for life sciences, this includes microarray, next generation sequencing, and mass spectrometry technologies. Later lectures will focus on an introduction to bioinformatics and its concepts. Students will develop essential bioinformatics skills and learn how to apply these skills into the design and analysis of their own experiments. Tutorials in this unit will strengthen the concepts and knowledge covered in the lectures, and allow students to trial several bioinformatics tools. Tutorials will provide students with practical examples and hand-to-hand guidance in tackling real high throughput genomics data. To get the most out of this unit, students should attend each lecture and tutorial where possible. Unit readings can be conducted depending on personal preferences: please either pre-read the contents prior to the lectures each week to give yourself a basis to understand the lecture content, or conduct the readings following the lectures to consolidate your knowledge of the content. This unit will require basic skills in statistical analysis and basic skills in using computers. Students are expected to engage in independent study, and develop critical thinking skills to apply the theory and concepts covered to practical situations. Tutorials will be conducted on the assumption that you have already engaged with the lecture material. Not doing so will greatly diminish the quality of the class discussions on the unit topics. Tutorial classes will involve small group discussions, interactive class demonstrations, and related interactive activities to enhance individual learning outcomes. Altogether, these activities will assist in your consolidation of the unit contents, and will provide you with the opportunity to learn how biotechnology and bioinformatics can be applied to future individual study.|
|Other Learning Experiences||Visit microbiome and agriculture research laboratories, expose to cutting-edge genome sequencing experiments and their applications in practical research.|
|Assessment||1. Display basic knowledge and understanding of core topics in bioinformatics, including those both in genomics and proteomics.
2. Demonstrate knowledge of theoretical and application bases underpinning genome sequencing, gene expression analysis, and qualitative and quantitative proteomics.
3. Explain key biotechnologies for modern molecular life sciences and understand the fundamentals and biology underpinning these technologies.
4. Reflect on and demonstrate critical thinking choosing correct technology for specific experiments.
The assessments in this unit consist of 3 components:
Mid-semester test - 20%
A data analysis report - 40%
End of semester examination - 40%
|Appears in these Minors||Bioinformatics
|Internet Access Requirements||Murdoch units normally include an online component comprising materials, discussions, lecture recordings and assessment activities. All students, regardless of their location or mode of study, need to have access to and be able to use computing devices with browsing capability and a connection to the Internet via Broadband (Cable, ADSL or Mobile) or Wireless. The Internet connection should be readily available and allow large amounts of data to be streamed or downloaded (approximately 100MB per lecture recording). Students also need to be able to enter into online discussions and submit assignments online.|