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Unit (2020)

Information on this page, including unit offerings, is from the 2020 academic year.

Pathological Basis of Disease (BMS314)

Organisational Unit Medical, Molecular and Forensic Sciences
Credit Points 3
Availability MURDOCH: S1-internal
Teaching Timetables Murdoch S1
Description This unit deals with the basic principles of general pathology. It covers all the key mechanisms of diseases such as thrombosis, cardiovascular disturbances, inflammation, cell and tissue death, diseases resulting from an aberrant in utero environment, and diseases of abnormal DNA processing such as neoplasia and inherited conditions. Using examples from human and animal disease the relationships between the varying pathological processes will be explored. Disease is discussed at both the naked eye, microscopic and molecular levels.
Unit Learning Outcomes At the completion of this Unit, you should be able to achieve the following theoretical and practical outcomes:
Theoretical Outcomes
1. Define each of the general pathological processes covered in this unit (hyperaemia, haemorrhage, oedema, thrombosis, acute inflammation, chronic inflammation, healing by regeneration and repair, cellular degeneration and death, adaptive tissue responses, pigment accumulation and storage diseases, calcification, neoplasia and teratology), explain the mechanisms and outline the pathways of progression (pathogenesis) of the disease.
2. Describe the typical gross and histomorphologic appearance and features of these pathological processes, and predict their sequelae and consequences for the patient.
3. Make appropriate use of the vocabulary and terminology used in the discipline of General Pathology to describe the pathogenesis of a tissue lesion or disease.

Practical Outcomes
4. Recognise and describe the key anatomical and histological features of the main organ systems of the body e.g. lung, liver, kidney, muscle, skin, nervous system, alimentary tract, pancreas.
5. Recognise and describe lesions in tissues at both the gross and microscopic levels, and link these with a pathological process.
6. You should be able to interpret the features you see to classify lesions according to: distribution, severity, nature of the change, timing and where possible suggest a possible cause (aetiology).
7. Demonstrate and understanding of some histochemical techniques used in the discipline of histopathology.
Timetabled Learning Activities Lectures: 3 hours per week; histopathology laboratories: 2 hours per week.
Unit Learning Experiences The approach to learning in this unit is to utilise a mix of structured learning activities (lectures and practicals), semi-structured review sessions and individual assessment tasks. A variety of texts, lecture notes and on-line resources are recommended for further learning, and summaries of all formal learning material will be made available on-line for review. Assessment tasks are designed to test the depth of understanding of the principals and language of general pathology, and to reflect a 'real life' task of a biomedical scientist in writing a grant proposal for research funding.
Assessment Assessments include a mix of supervised exams, quizzes and an individual writing task. The final exam (60%) is a supervised exam designed to test specific knowledge of the topics covered in the unit, and will also cover the practical lesion description elements of the unit. The individual written assessments include a short essay component to the final exam as well as a research grant synopsis covering an area of research chosen by the student (20%). Additional on-going assessment will be provided by a series of on-line quizzes covering each major topic throughout the semester (20%). In all cases, detailed information is given during semester about expectations and marking, and students are encouraged to raise questions during review and practical sessions.
Prerequisites BMS264/BMS206 OR BMS321 OR concurrent enrolment in BMS321.
Exclusions Students who have successfully completed BMS360 Mechanisms of Disease or ANS313 Pathology and Diseases of Production Animals cannot enrol in this unit for credit.
Previously 2015: 'Mechanisms of Disease'
Appears in these Courses/Majors:
see individual structures for context
Bachelor of Laboratory Medicine (BLabMed) [New in 2020]
Biomedical Science (BSc) [New in 2020]
Chiropractic Science + Clinical Chiropractic (BSc)+(BClinChiro) [New in 2015]
Appears in these Minors Biomedical Science
Internet Access RequirementsMurdoch units normally include an online component comprising materials, discussions, lecture recordings and assessment activities. All students, regardless of their location or mode of study, need to have access to and be able to use computing devices with browsing capability and a connection to the Internet via Broadband (Cable, ADSL or Mobile) or Wireless. The Internet connection should be readily available and allow large amounts of data to be streamed or downloaded (approximately 100MB per lecture recording). Students also need to be able to enter into online discussions and submit assignments online.


Unit Coordinator
Associate Professor Phil Stumbles
Associate Professor Pathology

Murdoch Campus
t: 9360 6201
e: P.Stumbles@murdoch.edu.au
o: 250.2.004 - Building 250, Murdoch Campus
Unit Contacts

MURDOCH: S1-Internal
Associate Professor Phil Stumbles
Associate Professor Pathology

Murdoch Campus
t: 9360 6201
e: P.Stumbles@murdoch.edu.au
o: 250.2.004 - Building 250, Murdoch Campus
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